The postings above will show you that there are only a few .22 pistols to stay away from. On the positive side, Ruger will give you the most versatility and dependability. There are plenty of parts and upgrades for Mark I, II, and III, and the 22/45. Pawn shops are a good place to find bargains (and overpriced guns-be sure to haggle). Feel the difference in the grip angle between the Marks and the 22/45- you have a choice. Want a particular barrel length? several to choose from in all those models.Want
I just put meps on my G27. Absolutley love them! Looked at all brands, came down to trijicon and meps. Found out over time the white around the trijicon vials wears off. Meps are sealed and won't do this. Go green/ green they stay brighter longer than any other color! D.