Because I'm old and came up with 1911's, I have never felt comfortable carrying a gun until it shoots at least 5 or 600 rounds without a failure.
When I got into Glocks I shot all kinds of ammunition out of them and after over 6000 rounds out of my two carry guns (21sf & 36) I have yet to find a brand or weight or type of round that does not shoot well out of a Glock.
Pick one and shoot it. More than likely it will be fine. Any good name brand "self defense" round will be ok.
The benefit of shooting a 45 is the 230g bullet. But be sure to try a lighter round as it has an effect on felt recoil.
The Evil Captain Kirk