Another fan here of WSF. It's about the most accurate powder I have used in my 40s. Also, being a med burn rate, will likely keep you from getting into pressreu troubles.
"Given adequate penetration, a larger diameter bullet will have an edge in wounding effectiveness. It will damage a blood vessel the smaller projectile barely misses. The larger permanent cavity may lead to faster blood loss. Although such an edge clearly exists, its significance cannot be quantified".