All you have to do is look at why someone was stopped with a 22lr. Usually it is because the bullet destroyed something very vital, like the heart or aorta etc.....
Now use a round that consistently penetrates enough to reach that vital even if it has to go throw an arm or some other soft barrier.
Then you have to actually shoot that bullet so it hits the vital part.
Look at hard barrier performance if you are LE.
In the end 9/.40/.357sig/.45 all have what it takes to reach that vital through a soft barrier if you place your shot.
If you shoot someones heart with a 9mm or a .45 it isn't going to make any difference so I will take an added advantage and have more capacity.
Hard barrier performance is a different story.
Last edited by High Altitude; 01-25-2012 at 16:34..