For "service caliber" pistols (meant for SD/CCW) with muzzle velocities of 750-1300 fps, I've always just sighted the gun in for 25 yds.
Sighted-in like that, such a bullet will cross zero at about 10-13 yards (on its way "up" the trajectory) and then once again at the sighting-in range 25 yards (on its way "down" the trajectory) while never being more than about a quarter inch above or below the point of aim over the entire distance being traveled.
For those who CCW:
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Last edited by M 7; 01-29-2013 at 14:06..