One of the Wesson family of S&W back in the 30s used a .357 (6" IIRC) to take just about every kind of game on earth including most of the large clawed African stuff.
It may not be a .50 BMG but it's not a wimp load.
"And Shepherds we shall be. For thee, my Lord for thee. Power hath descended forth from thy hand, that our feet may swiftly carry out thy command. So we shall flow a river forth to thee and teeming with souls shall it ever be. In nomine Patris, et fili, et Spiritus Sancti. Amen."