Or this. In your night stand, you have a 22lr target pistol w/ 10shots, a 38sp 4" w/ 6shots of 148grLWC, one late night attacker, which do you grab to defend yourself or your family? Yeah, I doubt most would say 22lr. I can teach ANYONE to shoot a 38sp 4" gun effectively in one day. No diff headshot, just COM & go. You will have one chance to get it right, don't even think of handicapping yourself w/ a 22lr, foolish. As always, this is JMO, as teh OP was asking for opinions.
"Given adequate penetration, a larger diameter bullet will have an edge in wounding effectiveness. It will damage a blood vessel the smaller projectile barely misses. The larger permanent cavity may lead to faster blood loss. Although such an edge clearly exists, its significance cannot be quantified".
Last edited by fredj338; 02-12-2013 at 13:34..