Once we have shot through an animal, we have done all we can do. There are plenty of loads that will shoot through a deer in 44 magnum. But, they'll still have more recoil, blast and operating pressures than the 45 Colt and they'll still have a smaller, lighter bullet.
The 44 magnum is a great cartridge. IMHO, the 45 Colt is just better. I don't mind not finding hunting or self defense loads in 45 Colt at WalMart, I buy most of my ammo online. Besides, Wally World is phasing out their handgun from what I understand. It will be a non-issue soon enough.
P.A. Glocker Charter Member #48
Pennsylvania Constitution Article I, Section 21
The right of the citizens to bear arms in defense of
themselves and the State shall not be questioned.