Truth to tell, I haven't run across any actual shootings with any of the PDX rounds yet. In Winchester's Ranger series, the 127grain +P+ with ballistics similar to the 124 +P has amassed an extraordinary record on the streets of Orlando, while Los Angeles County is very pleased with the 147 grain Winchester Ranger.
Personally, I find the 127+P+ and 124+P seem to cause dramatically wider wound channels in flesh as opposed to gelatin, and are less often associated with shoot-throughs. The 147 grain subsonic is very accurate, and if you don't reload it's much easier to find analog training ammo with roughly the same weight/velocity to duplicate point of aim/point of impact. I go with 127 or 124 at a nominal 1250 fps myself, but YMMV.
best wishes for the new year,