The short answer is yes.
The long answer is depending on what caliber conversion you own and what caliber you want to load.
Take for instance 9mm and 40 sw. they share the same shell plate so you only have to buy new buttons and funnel instead of a complete caliber conversion.
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If a man neglects to enforce his rights, he cannot complain if, after a while, the law follows his example.
Without idiots, there would be no baseline for common sense.
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"Given adequate penetration, a larger diameter bullet will have an edge in wounding effectiveness. It will damage a blood vessel the smaller projectile barely misses. The larger permanent cavity may lead to faster blood loss. Although such an edge clearly exists, its significance cannot be quantified".
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