Glock Talk
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11-27-2012, 06:48
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#1
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Senior Member
Join Date: Aug 2002
Location: Virginia
Posts: 10,470
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::FDA:: Don't take your drugs with grapefruit juice!
::FDA::
Don't take your drugs with grapefruit juice!
That's not a bad rule to follow, because enough drugs have been prove to have some very harmful side effects if you do.
Side effects from taking them with grapefruit juice can be as severe as death.
85 oral medications, including pills for heart problems, pain and psychiatric problems have been put on the "no Grapefruit juice" list:
A-C
Alfentanil (oral)
Amiodarone
Apixaban
Atorvastatin
Buspirone
Clopidogrel
Crizotinib
Cyclosporine
D-F
Darifenacin
Dasatinib
Dextromethorphan
Domperidone
Dronedarone
Eplerenone
Erlotinib
Erythromycin
Everolimus
Felodipine
Fentanyl (oral)
Fesoterodine
H-P
Halofantrine
Ketamine (oral)
Latatinib
Lovastatin
Lurasidone
Maraviroc
Nifedipine
Nilotinib
Oxycodone
P-Z
Pazopanib
Pimozide
Primaquine
Quinine
Quetiapine
Quinidine
Rilpivirine
Rivaroxaban
Silodosin
Simvastatin
Sirolimus
Solifenacin
Sunitinib
Tacrolimus
Tamsulosin
Ticagrelor
Triazolam
Vandetanib
Venurafenib
Verapamil
Ziprasidone
__________________
Correctional and Therapeutic Mayhem Administrator EMERITUS
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GLOCK CERTIFIED ARMORER
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11-27-2012, 07:20
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#2
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Senior Member
Join Date: Mar 2008
Posts: 2,257
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besides grapefruit being disgusting anyway. what on earth in it makes it have such negative effects with so many drugs?
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11-27-2012, 07:28
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#3
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Senior Member
Join Date: Oct 2004
Location: Ohio
Posts: 2,678
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Seen a episode of the Dr. Oz show last week and he was talking about diets for loosing weight,and said Grapefruit juice was good for a weight reduction.He didn't mention any caution about not drinking Grapefruit just if taking some Medications. So much for the all wise Dr. Oz. 
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11-27-2012, 07:38
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#4
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Lifetime Membership
Badass Member
Join Date: Aug 2008
Location: Lubbock/Amarillo, TX
Posts: 6,117
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Quote:
Originally Posted by Atomic Punk
besides grapefruit being disgusting anyway. what on earth in it makes it have such negative effects with so many drugs?
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It is a potent inhibitor of Cytochrome P450 enzyme 3A4 that plays a big role in the hepatic metabolism of a lot of drugs. If you drink grapefruit juice your body cant get rid of the drug thus it accumulates to toxic levels.
__________________
Sent from a payphone in a whorehouse in Mexico.
__________________
~RIP Chad
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11-27-2012, 07:44
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#5
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Widow's Son
Join Date: Apr 2001
Location: western PA
Posts: 6,343
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^^ Yep! I knew this as it's written on my meds label. Thanks for posting for those who didn't know. tom.
__________________
N.R.A. LIFE MEMBER
SPES MEA IN DEO EST
Thig crioch air an t-saoghal ach mairidh gaol agus ceòl The world will come to an end but music and love will endure
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11-27-2012, 07:50
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#6
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Senior Member
Join Date: Mar 2008
Posts: 2,257
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Quote:
Originally Posted by Travclem
It is a potent inhibitor of Cytochrome P450 enzyme 3A4 that plays a big role in the hepatic metabolism of a lot of drugs. If you drink grapefruit juice your body cant get rid of the drug thus it accumulates to toxic levels.
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that is really interesting. may or may not mention that to people i know that eat grapefruit 
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11-27-2012, 07:59
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#7
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Gold Membership
Directiv 10-289
Join Date: Oct 2008
Location: Missouri, East of KC
Posts: 5,623
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And grapefruit itself.
Back in the early 1990s, my parents sent us a case of Ruby Red grapefruit, and we ate a lot of it.
My wife semi-ODed on her normal meds. We researched it and went back to her doctor with the news. He didn't know. few people really did.
A couple of weeks ago, she forgot and bought some GF juice. She started feeling dizzy the next day.........
__________________
"I am wracked with such hearty guffaws that in addition to rolling to and fro on the floor, my posterior has separated itself from my body."
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11-27-2012, 08:56
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#8
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Senior Member
Join Date: Feb 2007
Location: Texas
Posts: 1,801
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Am I the only one who always thought you were supposed to take your drugs with whiskey?
__________________
17 + 30 = 21
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11-27-2012, 09:34
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#9
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Señor Member
Join Date: Feb 2005
Location: Back in Podunk
Posts: 8,631
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The mystery of how and why people drink grapefruit juice to begin with remains...
__________________
I don't really think Atlas is going to shrug. It's just a vain dream of mine.
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11-27-2012, 10:08
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#10
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Senior Member
Join Date: May 2006
Location: Near Central US
Posts: 2,853
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Quote:
Originally Posted by lethal tupperwa
::FDA::
Don't take your drugs with grapefruit juice!
That's not a bad rule to follow, because enough drugs have been prove to have some very harmful side effects if you do.
Side effects from taking them with grapefruit juice can be as severe as death.
85 oral medications, including pills for heart problems, pain and psychiatric problems have been put on the "no Grapefruit juice" list:
A-C
Alfentanil (oral)
Amiodarone
Apixaban
Atorvastatin
Buspirone
Clopidogrel
Crizotinib
Cyclosporine
D-F
Darifenacin
Dasatinib
Dextromethorphan
Domperidone
Dronedarone
Eplerenone
Erlotinib
Erythromycin
Everolimus
Felodipine
Fentanyl (oral)
Fesoterodine
H-P
Halofantrine
Ketamine (oral)
Latatinib
Lovastatin
Lurasidone
Maraviroc
Nifedipine
Nilotinib
Oxycodone
P-Z
Pazopanib
Pimozide
Primaquine
Quinine
Quetiapine
Quinidine
Rilpivirine
Rivaroxaban
Silodosin
Simvastatin
Sirolimus
Solifenacin
Sunitinib
Tacrolimus
Tamsulosin
Ticagrelor
Triazolam
Vandetanib
Venurafenib
Verapamil
Ziprasidone
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Add Warfarin to the list. Probably a number of GTers on it. Alters how it works and makes the INR tests mostly useless, culminating in prescribed doses being way to high or to low. Results can be devastating, as my wife found out after the hospital called me a 6:00 in the morning to get there NOW if I wanted to see her again.
__________________
fwm
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11-27-2012, 11:30
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#11
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Widow's Son
Join Date: Apr 2001
Location: western PA
Posts: 6,343
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Quote:
Originally Posted by SMOKEin
Am I the only one who always thought you were supposed to take your drugs with whiskey?
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No, you aren't but it's Whisky. tom. 
__________________
N.R.A. LIFE MEMBER
SPES MEA IN DEO EST
Thig crioch air an t-saoghal ach mairidh gaol agus ceòl The world will come to an end but music and love will endure
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11-27-2012, 11:41
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#12
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Get off my lawn
Join Date: Aug 2001
Location: Taunton, MA
Posts: 46,227
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We took druuuuugs and grapefruit juice. Look what happened to us!
(OK, maybe we just came from the eye doctors. LOL)
__________________
The truth is you're the weak. And I'm the tyranny of evil men. But I'm tryin', Ringo. I'm tryin' real hard to be the shepherd.
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11-27-2012, 11:48
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#13
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Senior Member
Join Date: Nov 2005
Posts: 5,035
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Quote:
Originally Posted by SMOKEin
Am I the only one who always thought you were supposed to take your drugs with whiskey?
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Actually, when taking drugs, it's vodka, that should be used!
Whiskey, is actually, medicine, on it's own!
__________________
If guns kill people, then, I can blame my pencil on my spelling!
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11-28-2012, 06:58
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#14
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Lifetime Membership
Badass Member
Join Date: Aug 2008
Location: Lubbock/Amarillo, TX
Posts: 6,117
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Quote:
Originally Posted by fwm
Add Warfarin to the list. Probably a number of GTers on it. Alters how it works and makes the INR tests mostly useless, culminating in prescribed doses being way to high or to low. Results can be devastating, as my wife found out after the hospital called me a 6:00 in the morning to get there NOW if I wanted to see her again.
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Yes, Warfarin is definitely on the list.
__________________
Sent from a payphone in a whorehouse in Mexico.
__________________
~RIP Chad
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